Cure MSA

Country specific patient information


Principal Investigator:
Prof Latchezar Traykov, MD, PhD, DSc

Head of Department of Neurology
University Hospital Alexandrovska, Executive Director
1, Georgi Sofiiski str,
1431 Sofia, Bulgaria

Contact person:
Dr Mariya Petrova, MD, PhD

Assisstant Professor
Department of Neurology
University Hospital Alexandrovska
1, Georgi Sofiiski str,
1431 Sofia, Bulgaria
e-mail: dr.mpetrova(at)

Expertise of the participating organization:


The Movement Disorders Group at the university hospital Alexandrovska, Sofia as long been recognized as one of the leading clinical and research group in Bulgaria with primary focus on neurodegenerative disorders in aged population. During the last years our team has been working especially in the field of neurodegenerative disorders with Parkinsonism, developing several projects for clinical, neuropsychological and genetic markers for early diagnosis of dementia in Parkinson’s disease and also for the earliest possible differentiation from Dementia with Lewy bodies and Essential tremor. In the domain of atypical Parkinsonism the team has directed his attention to the appearance and development of the earliest and specific cognitive and behavior changes in Multiple system atrophy, Progressive supranuclear palsy and Corticobasal degeneration. The team received several awards of the European and world’s congresses for his work in the field of Parkinson’s disease.

Recent publications relevant to the EMSA-SG:


Petrova M, Raycheva M, Zhelev Y, Traykov L. Executive functions deficit in Parkinson's disease with amnestic mild cognitive impairment. Am J Alzheimers Dis Other Demen. 2010 Aug;25(5):455-60.


Mehrabian S, Duron E, Labouree F, Rollot F, Bune A, Traykov L, Hanon O. Relationship between orthostatic hypotension and cognitive impairment in the elderly. J Neurol Sci. 2010 Dec 15;299(1-2):45-8.


Petrova M., Raycheva M., Mehrabian S., Zhelev Y., Angov G., Traykov L. Relationship between depression and cognitive deficits in Parkinson’s disease patients with mild cognitive impairment. Bulgarian Neurology, 2010, 10, 3, 122-125.


Dalla Barba G, Traykov L, Baudic S. Neuropsychological examination in dementia. Handb Clin Neurol. 2008;89:15-33.


Petrova M, Raycheva M, Jelev Y, Mehrabian S, Petrova I., Krushkov H., Elenkov Ch., Traykov L. Neuropsychological evaluation in early stage of Parkinson’s disease dementia and  dementia with Lewy bodies. Bulgarian Neurology, 2008, 3, 112-115.


Traykov L, Bayle AC, Latour F, Lenoir H, Seux ML, Hanon O, Péquignot R, Bert P, Moulin F, Cantegreil I, Wenisch E, Batouche F, Mehrabian S, Rotrou J, Rigaud AS. Apolipoprotein E epsilon4 allele frequency in elderly depressed patients with and without cerebrovascular disease. J Neurol Sci. 2007 Jun 15;257(1-2):280-3.


Petrova M, Traykov L, Raycheva M, Mehrabian S, Jelev Y, Maslarov D. Specifics of the cognitive profile in Multiple system atrophy. Bulgarian Neurology, 2007, 7, 1, 33-36.


Baudic S, Maison P, Dolbeau G, Boissé MF, Bartolomeo P, Dalla Barba G, Traykov L, Bachoud-Lévi AC. Cognitive impairment related to apathy in early Huntington's disease. Dement Geriatr Cogn Disord. 2006;21(5-6):316-21.


Petrova M., Traykov L., Raycheva M., Grigorova O., Cherninkova S., Jelev Y., Mehrabian S. Cognitive impairment in а patient with Progressive Supranuclear Palsy. Bulgarian Neurology, 2006, 6, 2, 98-101.


Traykov L., Petrova M., Raycheva M., Mehrabian S. Cognitive impairment in а patient with Corticobasal degeneration. Bulgarian Neurology, 2006, 6, 3, 149-152.